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filingDate 2011-07-21^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-06-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f27ed2e0eda4f57e21dcf1b6f804da5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c15ad51dd82697cc7f6aa75ff3647d
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publicationDate 2015-06-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2553564-C2
titleOfInvention Genetically modified bacterial strain wsj-ia i, producing isovaleryl spiramycin with high content and high output
abstract FIELD: chemistry. n SUBSTANCE: present invention relates to biotechnology and is a genetically modified strain of Streptomyces thermotolarences WSJ-IA, which produces isovaleryl spiramycin I. The present invention also discloses a method of producing said strain. The method includes steps of constructing a recombinant plasmid comprising a double gene ist-acyB2 and transforming the plasmid into the isovaleryl spiramycin I - producing strain WSJ-IA. The invention also discloses a method of producing isovaleryl spiramycin I by culturing the Streptomyces thermotolarences WSJ-IA strain in a culture medium. n EFFECT: present invention increases the output of the obtained isovaleryl spiramycin I. n 3 cl, 3 dwg, 5 tbl, 4 ex
priorityDate 2010-07-23^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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