http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2555502-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c73b81f32b8be45a1ea5cb361997fc0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L17-10 |
filingDate | 2013-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-07-10^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f1e2d372ec102f2960650217ceccf58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7642926782d9a86127f2d95387d95b6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_814a0e5cd8d774fd2790df7c6d8c2a9e |
publicationDate | 2015-07-10^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2555502-C2 |
titleOfInvention | Suture material with antithrombotic coating |
abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine and represents a suture material with an antithrombotic coating consisting of a polypropylene carrier suture coated with 3-hydroxybutyrate/3-hydroxyvalerate (PHBV) copolymer in the concentration of 1-6%, and at least one antithrombotic substance; the suture material coating is fixed by a chemical reaction: at the first stage, the carrier suture is immersed into a biopolymer for 10 minutes and dried at room temperature for 3 hours in a dust-free chamber, and then for 1 hour in mixed air and ozone; the suture is kept for 5 hours in the methacryloyl chloride vapour at a temperature of 85-90°C; the second stage involves the suture modification with heparin (1,000 units/ml); the suture is immersed into heparin at a temperature of 2-5°C for 10 hours and for 14 hours into heparin at room temperature; the suture material is finally dried in the dust-free chamber at room temperature until completely dry. n EFFECT: invention provides higher hemo- and biocompatibility of the retention suture material, as well as higher antithrombotic characteristics by the multilayer modification of the retention suture by the biodegradable polymer and heparin. n 3 cl, 1 tbl, 3 dwg |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-181548-U1 |
priorityDate | 2013-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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