| abstract |
FIELD: biotechnology. n SUBSTANCE: invention relates to biotechnology, specifically to an artificial nucleic acid molecule. Invention further relates to the use of such an artificial nucleic acid molecule encoding therapeutic peptides or proteins in medicine for gene therapy and / or genetic vaccination. n EFFECT: synergistic effect due to the presence of 3'UTR albumin gene and 5'UTR element, which is derived from the TOP gene, increases the stability and prolongs the expression of the encoded protein. n 83 cl, 30 dwg, 5 tbl, 5 ex |