http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2717986-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_930dbfaf9af0027ba4121c0a7c4288de |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 |
| filingDate | 2014-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e1161266b375a2c7c327545d74ee048 |
| publicationDate | 2020-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2717986-C2 |
| titleOfInvention | Artificial molecules of nucleic acid |
| abstract | FIELD: biotechnology.SUBSTANCE: invention describes an artificial nucleic acid molecule for genetic therapy or genetic vaccination, comprising at least one open reading frame (ORF) coding a therapeutic peptide; and at least one 3'-untranslated region (3'-UTR) element, which contains a nucleotide sequence derived from 3'-UTR of the ribosomal protein gene or from the functional version of 3'-UTR of the ribosomal protein gene, wherein said functional variant is at least 80 % identical to said 3'-UTR gene of ribosomal protein; and 5'-untranslated region (5'-UTR), as additional 5'-end of element, where 5'-UTR is 5'TOP-UTR, which does not contain 5'-TOR motive. Application describes an artificial nucleic acid molecule containing at least one open reading frame and at least one 3'-untranslated region (3'-UTR) element which contains a nucleotide sequence derived from 3'-UTR of the ribosomal protein gene.EFFECT: artificial nucleic acid molecules are disclosed; invention can be used in gene therapy and/or genetic vaccination.24 cl, 9 dwg, 5 tbl, 1 ex |
| priorityDate | 2013-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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