http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2741911-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5e87b1c74d79698e7133a56fbe8a16e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2017-04-24^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-29^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d38440e3a5035e15c605c9eb8debc25a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b67f63ff0020bc8e383b0766a17572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ebff454afdeff92ae88abfe8f17e3fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9250f837cf9a86d4a22ff55c631c6879 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a583c3784169b3b2edaad473da46936 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a0b88d332b9e0f2767386ed76f6a5fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9852bcd79ba6e6168a17dd23ec43e26c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae026d29da9517455f0fceef9268f3ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e406fa370c04e0c4fd919cbcc206dc7 |
| publicationDate | 2021-01-29^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2741911-C2 |
| titleOfInvention | New substituted imidazopyridine compounds as indoleamine-2,3-dioxygenase and/or tryptophan-2,3-dioxygenase inhibitors |
| abstract | FIELD: pharmaceuticals.SUBSTANCE: invention relates to a compound of imidazopyridine of formula (I),where: each of R1and R2is H; one of R3and R6is H, and the other is Y1; each of R4and R5is independently selected from a group consisting of (1) H, (2) halogen, (3) C1-6-alkyl, optionally substituted with one to three halogen atoms, and (4) C1-6-alkoxy, optionally substituted with one to three halogen atoms; Y1is a group having the following formula:the dotted lineis an optional double bond; Q is -C(Ra)(Ra')-, -N(Ra)- or -O-; T is -C (Ra)(Ra')- or -N(Ra)-; Rais selected from a group consisting of (1) H, (2) C1-6-alkyl, and (3) phenyl; wherein each of alkyl and phenyl is optionally substituted with one substitute independently selected from halogen and 6-member heteromonocyclic group containing one ring heteroatom, selected from oxygen; Ra'is selected from a group consisting of (1) H and (2) C1-6-alkyl; Rbrepresents C 1-6 -alkyl; each of R c and R d is independently selected from a group consisting of (1) H, (2) C1–6-alkyl, and (3) oxo; m is 0, 1 or 2; n equals 0, 1 or 2; and p is 0 or 1, which are inhibitors of indolamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes; also disclosed is use of compounds in potential treatment or prevention of development of IDO- and/or TDO-associated disease or disorder, compositions containing these compounds, and use of compounds in potential treatment or prevention of developing IDO- and/or TDO-associated disease or disorder.EFFECT: novel substituted imidazopyridine compounds as inhibitors of indolamine-2,3-dioxygenase and/or tryptophan-2,3-dioxygenase.17 cl, 32 ex, 6 tbl |
| priorityDate | 2016-04-29^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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