abstract |
FIELD: immunology. n SUBSTANCE: antibody is proposed that specifically recognizes human IL-13RA2, as well as a multifunctional immunoconjugate and a chimeric antigen receptor based on such an antibody. In addition, nucleic acid, an expression vector, a host cell, a virus, an immune cell, a pharmaceutical composition, a set and application are considered. n EFFECT: this invention can find further application in the therapy of tumors expressing human IL-13RA2. n 20 cl, 24 dwg, 1 tbl, 12 ex |