| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f00b503b4045fc858275a7c77e27c087 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1998-06-22^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e437aa3d64c0042007aa13759d38fa6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc921db55ff811629a5cf328e7da323f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a11bece7929dd45b4d937d515918d004 |
| publicationDate |
2000-08-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
SK-170299-A3 |
| titleOfInvention |
Aminospiro piperidine quinazoline derivatives, process and intermediates to their preparation, pharmaceutical compositions them containing and their use |
| abstract |
There are provided novel compounds of formula (I) wherein A represents an aromatic carbocyclic ring or a 5- or 6-membered heterocyclic aromatic ring containing 1 to 3 heteroatoms which may be the same or different and are selected from O, N and S; X represents -(CH2)n- wherein n represents zero or 1; and R<1>, R<2> and R<3> are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and tautomers thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain. |
| priorityDate |
1997-07-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |