abstract |
9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines of formula (I) and compositions of formula (III) as intermediates for production of compositions of formula (I) by reaction of composition of formula (III) with nucleofil compound of formula WH in polar aprotic diluent and under inert atmosphere. Method for production of compositions of formula (I) by reaction of compositions of formula (I) with chloride of acid of general formula (R,R,W)C-C(=O)X in inert diluent and polar aprotic diluent with the presence of base. Pharmaceutical and veterinary preparations based on compositions of formula (I) are antibacterial agents. |