abstract |
The present invention relates to compounds of the Formula, , wherein R1, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, X, Y, W, U, Z, m and n are as defined. Compounds of the Formula I have activity inhibiting production of A β-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I. |