abstract |
The present invention relates to novel pyridines that can be used as SHP2 inhibitors Derivatives (as shown in structural formula I), and their synthesis methods and treatment, prevention or prevention of diseases or disorders mediated by SHP2 active agents. Further, the present invention relates to fusion heterocyclic derivatives used as SHP2 inhibitors, and methods for preparing the compounds and methods for treating, preventing or preventing diseases or discomforts mediated by SHP2 active agents. |