| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c564804e4e89ea0871bbeefd81569950 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 |
| filingDate |
2019-04-23^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e31c09602a147e08060d2818bc723a20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a553b7cc7b23f97b97f70138722f7074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c16f740931ed38a60dff00f8e4ca885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50dec44c55232f5887d79e75743eec42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c8c55f5d83ec1979ee66e058bc64140
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_495d3fa6242ca3b5cbcbc798355af98d |
| publicationDate |
2020-01-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-202003470-A |
| titleOfInvention |
Method for the hydrolysis of quinolonecarboxylic esters |
| abstract |
Quinolonecarboxylic esters of the general formula (II) are hydrolyzed to quinolonecarboxylic acids of the general formula (I): n n The method comprises the step A): A) reacting compounds of the formula (II) with a mixture comprising acetic acid, sulfuric acid and water In step A), 30 to 40 mol of acetic acid, 0.3 to 1 mol of sulfuric acid and 0.9 to 2.5 mol of water are used per mole of compounds of the formula (II). The method is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin. |
| priorityDate |
2018-04-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |