http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-509698-B

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filingDate 1995-06-09^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-11-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d77e5557602b65563c826fe481ab6690
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a32adfb9a6925fadc53c831f8f9b4197
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publicationDate 2002-11-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-509698-B
titleOfInvention Inhibitors of interleukin-1β converting enzyme
abstract The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against interleukin-1 mediated diseases, including inflammatory diseases, autoimmune diseases and neurodegenerative diseases. This invention also relates to methods for inhibiting ICE activity and methods for treating interleukin-1 mediated diseases using the compounds and compositions of this invention.
priorityDate 1994-06-17^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID767
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF1MWT5
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6342
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID8418
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419527252
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID420433698
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID411652170
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID448670727
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID449102015
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP13190
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID164912
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419520471
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID66854455
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID20330366
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3032732
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