| abstract |
1,4-substituted cyclic amine derivatives of the following formula, (wherein A, B, C, D, T, Y, Z: methenyl or N, R1-R5: substituent, n: 0 or 1-3, m: 0 or 1-6, p: 1-3), which have serotonin antagonism effect and can be used as a clinical medicine, particularly a treating, ameliorating or prophylactic agent for convulsion paralysis or central relaxant to improve muscle tonus. |