http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I290133-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac3eca7fa2f8ecd6ea05588b14520fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3d85238f30ab01379398800c900c6f9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 |
| filingDate | 2005-04-19^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-11-21^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dd2e29af59f131fe45f56516e70918d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c736d29cc5c479ff8df52f9cdb2b7a14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_475c865a346d67ce3c1bbedb5d18b897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf52eb86bbd77e4e45f8ff03fd14b2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d8474260ccce3dcdcb38559912d418 |
| publicationDate | 2007-11-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I290133-B |
| titleOfInvention | Process for preparation of tamsulosin and its aralkylamine derivatives |
| abstract | The present invention discloses a new process for the synthesis of tamsulosin and its aralkylamine derivatives, especially (R)-(-)-5-{2-[2-(2-alkoxyphenoxy) ethylamino] propyl}-2-alkoxybenzenesulfonamides having the following formula 1 (where R1 and R2 represent C1-C4 alkyl groups) and their hydrochloride thereof, and other various pharmaceutical used salts. Tamsulosin hydrochloride (R1=Et, R2=Me, in its hydrochloride salt form) is an antagonist of alpha-A adrenoceptors in the prostate. Tamsulosin HCl occurs as white crystals, which melt with decomposition at approximately 230 DEG C. It is sparingly soluble in water and in methanol, slightly soluble in glacial acetic acid and in ethanol, and practically insoluble in ether. |
| priorityDate | 2005-04-19^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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