abstract |
The present invention relates to a substituted nitrogen-containing bicyclic heterocyclic ring of formula (I),n n n n n n n n n n Wherein Z is CH 2 or NR 4 and X, R 1 , R 2 , R 4 , R 6 , R 7 and n are as defined in the specification. These compounds are suitable for treating disorders or diseases mediated by the activity of MDM2 and / or MDM4 or a variant thereof. |