Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d129195d35f178edd75fb75e7d8f5fd |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate |
2015-02-06^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-11-06^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b36ae9e0f4ee2434f7e1edf8d27149 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb52eb0a9750afd89f7635f2f71b9e53 |
publicationDate |
2018-11-06^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10118903-B2 |
titleOfInvention |
Aminotriazole-based KDM1A inhibitors as epigenetic modulators |
abstract |
In some aspects, the present invention provides compounds of the formula (IV), wherein the variables are as defined herein, which may be used as inhibitors of histone demethylase or spermine oxidase. Also provided herein are pharmaceutical compositions of the compounds and methods using the compounds in the treatment of diseases such as cancer and cardiovascular disease. |
priorityDate |
2014-02-07^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |