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filingDate 2017-07-19^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a910ddeeae0ecbda30d07e34d476d39c
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publicationDate 2019-02-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10209248-B2
titleOfInvention Multiplex immuno screening assay
abstract The present invention provides an immunoassay leading to the rapid and simultaneous detection of antibodies to a wide range of infectious pathogens in biological fluids of infected patients. This immunoassay involves the covalent and oriented coupling of fusion proteins comprising an AGT enzyme and a viral antigen on an identifiable solid support (e.g. fluorescent microspheres). The thus obtained antigen-coupled microspheres show enhanced capture of specific antibodies as compared to antigen-coupled microspheres produced by standard amine coupling procedures.
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