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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5e4219330649ad5d5841d1c1e72efa
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-045
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
filingDate 2017-04-18^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-03-26^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d198d426fc15cf02475ea2ac5f2bdd0
publicationDate 2019-03-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10239914-B2
titleOfInvention In-situ solvent recycling process for solid phase peptide synthesis at elevated temperatures
abstract An improvement of deprotection in solid phase peptide synthesis is disclosed. The method includes the steps of adding the deprotection composition in high concentration and small volume to the mixture of the coupling solution, the growing peptide chain, and any excess activated amino acid from the preceding coupling cycle; and without any draining step between the coupling step of the previous cycle and the addition of the deprotection composition for the successive cycle; and with the coupling solution at a temperature of at least 30° C.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019194246-A1
priorityDate 2015-10-23^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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