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filingDate 2017-05-24^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-04-02^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2111775ac549465d0622d16d571800c8
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publicationDate 2019-04-02^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10246713-B2
titleOfInvention TMPRSS6 iRNA compositions and methods of use thereof
abstract The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6 and methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as β-thalassemia or hemochromatosis.
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priorityDate 2014-11-24^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226400074
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA9HRV7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP13726
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID118661635
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID379992
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439357
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100033826
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID89858605
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226405489
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3037556
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID81649
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16176
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136594144
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID66535
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4WIW2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA6UUN9
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID177700
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID20604
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0JL93
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID89858513
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226413602
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11005
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB1HVE6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA3PFE3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1SUW6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0A6I8RCQ3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP02787
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398727
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID421329125
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA2RIM8
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID395103
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID413533255
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID421329129
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0S2N7
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136594132
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID421329174
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154404672
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID89858596
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136594134
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID431268333
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID701930
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154404673
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33824
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID89858597
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID431268335
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226393686
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB1YD06
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154404674
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136594136
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID431268340
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID411288237
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA6URW1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID613079
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4YVM6
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID449005
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA5ITK0
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID431268341
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID89858653
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID431268342
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA7ILC5

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