http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10301631-B2

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filingDate 2018-06-06^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-28^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdef2c64b56c41c22b051350bf6118d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_219b8dfdbd61e5a824418bbf046237e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b478a0168e830453c57143e99aa98af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68819ec9d22f92e8293e2f60fb98d53c
publicationDate 2019-05-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10301631-B2
titleOfInvention Biological indicator
abstract This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
priorityDate 2014-10-13^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6343933
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415825448
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21140642
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226585682
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226647614
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419483177
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID2733782
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID228637148
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A3I5
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC7ASJ5
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A341
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC7H7H2
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