| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cc860b9101f7cfe92516505014a9c01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-711 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2015-11-23^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-08-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3498133ff84cea6481b07ff587f1a3c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df257a86d195d70ef04dc71f3579075a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63e9a18b780ad476a97a63d988097c64 |
| publicationDate |
2019-08-27^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10393731-B2 |
| titleOfInvention |
Cellular-based method for determining the biological activity of defibrotide |
| abstract |
The present invention relates to cell-based methods for determining the biological activity of defibrotide. In particular, the invention provides a method for assessing the potency of defibrotide by assessing the viability of mammalian cells in the presence of at least one cytotoxic agent and one or more concentrations of defibrotide. Such methods are particularly useful for standardizing pharmaceutical compositions comprising defibrotide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022234101-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11236328-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746348-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11085043-B2 |
| priorityDate |
2014-11-27^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |