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filingDate 2018-09-25^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-04-07^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-04-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10610585-B2
titleOfInvention Methods and compositions for treating and preventing HIV
abstract Methods and compositions are provided that can be used to vaccinate against and treat HIV. Specifically contemplated are vaccine compositions and methods of using these compositions treat HIV in patients. Aspects of the disclosure relate to an anti-CD40 antibody-HIV antigen fusion protein comprising (i) an anti-CD40 heavy chain (HCD40)-HIV antigen (Ag) fusion protein comprising the formula: HCD40-Ag, wherein Ag is a polypeptide with at least 80% sequence identity to SEQ ID NO:1; and (ii) an anti-CD40 light chain (LCD40).
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