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filingDate 2013-05-30^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-12-15^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-12-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10866249-B2
titleOfInvention Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
abstract The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
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