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filingDate 2016-03-25^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3189f55593fe96cfc48fa1083258140
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5400110cefb5d1b471604f14cd4475bd
publicationDate 2021-01-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10889646-B2
titleOfInvention Use of KIT inhibitors to condition subjects for a hematopoietic stem cell (HSC) transplantation
abstract Provided herein are compositions and methods related to conditioning a subject for a hematopoietic stem cell (HSC) transplantation using an inhibitor of a stem cell growth factor receptor (KIT). The compositions and methods described herein are particularly useful for a subject who is in need of a HSC transplantation and who is hypersensitive to at least one DNA damaging agent, e.g., a subject with fanconi anemia. Compositions and methods related to conditioning a fanconi anemia subject for HSC transplantation using an inhibitor of KIT are also provided herein.
priorityDate 2015-03-25^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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