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filingDate 2019-01-03^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65d4f4e514e13e7092d8cdfd6270d323
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publicationDate 2021-01-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10894808-B2
titleOfInvention Polypeptide ligands specific for plasma kallikrein
abstract The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are specific for the human and rat protease plasma kallikrein and are modified in one or two peptide loops to enhance potency and/or protease resistance.
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