http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913984-B2

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filingDate 2015-11-12^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-02-09^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_222e3c11108ccb49b61a9535e201fb99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cfe8c0b7a9165dd8bc483557473af19
publicationDate 2021-02-09^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10913984-B2
titleOfInvention Predicting genetically stable recombinant protein production in early cell line development
abstract The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Hist1h2bc, Egrl, BX842664.2/Hist 1h3c, Dhfr, Fgfr2, AC115880.11, Mmp10, Vsnll (optional), CU459186.17, El 30203 B14Rik, Cspg4, C1qtnf1, Foxp2, and Ptpre.
priorityDate 2014-11-12^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04406
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP17721
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0R2M2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID281626
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP24855
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HPB1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID461669
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID281181
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID680312
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO59841
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC3NGT6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0B879
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA5ULT9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8ZWK7
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12367
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID406367
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ971K2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP57384
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP51009
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415824599
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP09567
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1464
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9ESV6
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10029
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID32545
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID42008
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00639
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8PTD3

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