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filingDate 2016-06-27^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-13^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e352506fbb6ca212ee3dcfd27b2ec99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad6a650e9856db48942310e68ab6cf86
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publicationDate 2021-04-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10973766-B2
titleOfInvention Oral pharmaceutical dosage form for the delivery of a peptide and/or protein
abstract The invention relates to an oral polymeric pharmaceutical dosage form which comprises a thermoresponsive eutectic composition which is solid at or about room temperature and fluid at or about body temperature, the eutectic composition mixed together with a crosslinking agent and an active pharmaceutical ingredient (API) to form an API loaded region; and a porous polymeric composition at least partially surrounding the API loaded region to protect the API when the dosage form is in a stomach of the human or animal body, the porous polymeric composition allowing the ingress of water to contact the crosslinking agent thereby facilitating the crosslinking agent to cause crosslinking of the porous polymeric composition, which crosslinked porous polymeric composition allows controlled egress of API via egress of fluid thermoresponsive eutectic composition at the intestine. In a preferred embodiment, the dosage form further comprises a coating there around.
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priorityDate 2015-06-26^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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