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filingDate 2018-02-16^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_015f91a51039a562462e3a20bff21cfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0395f093bcecba836d249d3ba855cfaf
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publicationDate 2021-04-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10980923-B2
titleOfInvention Implantable medical device with differentiated luminal and abluminal characteristics
abstract There are disclosed implantable medical devices and apparatus for treating implantable medical devices during production, so as to cause the implantable medical devices to have abluminal surfaces and luminal surfaces with different functional characteristics and in particular surface energies. The luminal surfaces of the medical device are preferably coated with carbon, so as to have a low surface energy, which reduces the risk of thrombi forming when implanted into a patient's vessels. The abluminal surfaces are treated so as to have a high surface energy, such that a therapeutic, preferably bioactive, material, such as a drug, can adhere to the abluminal surfaces and preferably without any need for a containment layer such as polymer or other matrix material. Once the therapeutic material has been delivered into the tissue wall, the stent can remain within the patient's vessel without leaving any delivery artefacts, as occurs with some prior art drug eluting medical devices.
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type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5362119
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16134267
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID428511112
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID702
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8623079
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP29598
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45427849
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID39251
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14442
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8623104
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID448718630
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID370
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3108
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226412961
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID410916410
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID433567914
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID1969
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1023373
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5280427

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