http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10981922-B2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9aa7fc2e2f0bb84d476da605da96ae95
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08
filingDate 2018-12-20^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa5911560fb31d1f82df6b70e6ab3605
publicationDate 2021-04-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10981922-B2
titleOfInvention Synthesis of lactams
abstract Methods for the synthesis of lactams are presented whereby a carboxylic acid of the formula HOOC—OR—NH-LG, wherein OR is an organic moiety and LG is a leaving group, is reacted with an acid, such as an organic acid, in particular a strong acid, and a dehydrating agent, which may be one in the same such as a strong acid anhydride, such that the amount of acid added allows for the desired transformation to take place without the loss of the leaving group (LG) before the cyclization, and recovering the lactam.
priorityDate 2012-04-26^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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