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filingDate 2020-09-15^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-08-31^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11104744-B2
titleOfInvention Genetic engineering of non-human animals for the production of chimeric antibodies
abstract The invention provides non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing transgenic cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention.
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