Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0b9b9c852ed547d55dd16c053269b29 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F13-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M31-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-624 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02C7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02C7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00 |
filingDate |
2020-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64dcfd2afb946b7f8d3aabcf10c8dcf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa85d3252375d99687b439f890b75976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f8a89da4d425eeaaa95186f34b05e4c |
publicationDate |
2021-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11173064-B2 |
titleOfInvention |
High-precision drug delivery by dual-domain ocular device |
abstract |
The present invention relates to a nanocomposite ocular device that can release drugs within a close distance to the ocular surface and provide controlled and sustained release of the drug at a constant rate. The device can achieve both optical and medical functions. The device comprises a drug, one or more reservoir domains, and a barrier layer configured to block the drug diffusion paths from the reservoir domain to the ocular surface in the eye of the subject, wherein the drug partitions between the reservoir domain and the barrier layer, and the equilibrium drug solubility in the reservoir domain is at least five folds higher than that in the barrier layer. |
priorityDate |
2016-09-30^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |