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filingDate 2018-12-19^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-01-25^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3605254fb74c310b0ae6fc67f2cc3e1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6f9c6c179ae5dec29c346f71a8e44d9
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publicationDate 2022-01-25^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11229613-B2
titleOfInvention Compositions including epinephrine microcrystals
abstract The invention provides compositions including epinephrine fine particles, including epinephrine nanoparticles or nanocrystals and epinephrine microparticles or microcrystals, and methods for therapeutic use of the compositions for the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine fine particles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required.
priorityDate 2013-03-22^^<http://www.w3.org/2001/XMLSchema#date>
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