| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d6f7da1e425c8a3ef1da21e08f4c196
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ffd5528fd07384d7b07ab484ed5b143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6929
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5115 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 |
| filingDate |
2020-06-16^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-02-15^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edbda603396c32661e01c326ace1077d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0536798668dff98a0f34fab33046202
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d68a20abdc5582eaf648a5c9db43dcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f8a73aa1f65d321f1f9ad0bc792271c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8089952224a0ccb87270150f80ed6d97 |
| publicationDate |
2022-02-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11246946-B2 |
| titleOfInvention |
Methods of treatment using ultrasmall nanoparticles to induce cell death of nutrient-deprived cancer cells via ferroptosis |
| abstract |
Described herein is a method of induced cell death via ferroptosis by nanoparticle ingestion. Moreover, the present disclosure describes the administration of high concentrations of ultrasmall nanoparticles at multiple times over the course of treatment in combination with a nutrient-depleted environment, thereby modulating cellular metabolic pathways to induce cell death by the mechanism ferroptosis. Ferroptosis involves iron, reactive oxygen species, and a synchronous mode of cell death execution. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541116-B1 |
| priorityDate |
2015-05-29^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |