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filingDate 2021-01-28^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-15^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-02-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11247971-B2
titleOfInvention Small molecule inhibitors of lactate dehydrogenase and methods of use thereof
abstract Provided is a compound of formula (I),in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.
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priorityDate 2014-12-29^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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