http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11275081-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2019-06-25^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-15^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3277608827af4b1e5ae60a9686f3b67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0188b66ef15447f2f29a1ca8e1bdd375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e466be6889829230e5702ea7f4682af |
| publicationDate | 2022-03-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-11275081-B2 |
| titleOfInvention | Pumilio domain-based modular protein architecture for RNA binding |
| abstract | A programmable modular protein architecture for RNA binding comprises a set of modules, derived from RNA-binding protein Pumilio, that can be concatenated into chains of varying composition and length. When bound into a chain, each module has a preferred affinity for a specific RNA base. The chains can bind arbitrary RNA sequences with high specificity and fidelity by varying the sequence of modules within the chains. Each module contains at least 6 amino acids, with the amino acids in positions 1 and 5 providing the preferred affinity for the specific base, and the amino acid at position 2 serving as a stacking unit between concatenated modules. The modules may have four canonic forms, each having a preferred affinity for a different base and characterized by the base with which it has affinity, the two amino acids that provide the affinity, and the amino acid that serves as a stacking unit. |
| priorityDate | 2015-01-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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