http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466000-B2

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filingDate 2021-11-08^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-10-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d966d9b5f989a48818ad720f40bc97f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af3010a98edb74d8b53752e556a3aa39
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publicationDate 2022-10-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11466000-B2
titleOfInvention Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component
abstract The present invention relates to a 6-(isooxazolidin-2-yl)-N-phenylpyrimidin-4-amine derivative, and a pharmaceutical composition for preventing or treating cancer comprising the compound as an effective component. The compound exhibits high inhibitory activity against an epidermal growth factor receptor (EGFR) variant, or wild-type or variants of one or more of ERBB2 and ERBB4, and thus may be usefully used in the treatment of cancers in which same are expressed. In particular, the compound exhibits excellent inhibitory activity on proliferation of lung cancer cell lines, and thus can be usefully used in the treatment of lung cancer.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022289733-A1
priorityDate 2019-03-19^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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