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filingDate 2018-04-06^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-10-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11466044-B2
titleOfInvention Neomycin and paromomycin derivatives
abstract The present disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6′, C2′ and/or C5″. The modifications impart favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits and increased selectivity, enabling systemic use of the compounds.
priorityDate 2017-04-07^^<http://www.w3.org/2001/XMLSchema#date>
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