http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11499053-B2

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filingDate 2021-05-10^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-15^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d3ee7d2ef4b53d21d9f29d0a5e20b14
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publicationDate 2022-11-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11499053-B2
titleOfInvention Water-soluble polymeric dyes
abstract Water soluble polymeric dyes and polymeric tandem dyes are provided. The polymeric dyes include a water solvated light harvesting multichromophore having a conjugated segment of aryl or heteroaryl co-monomers including branched non-ionic water soluble groups (WSG) comprising two or more water soluble polymers. In some cases, the branched non-ionic water soluble groups (WSG) of the present disclosure are capable of imparting solubility in water in excess of 50 mg/mL to the multichromophore. The polymeric tandem dyes further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are aggregation-resistant labelled specific binding members that include the subject water soluble polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
priorityDate 2016-12-12^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID53424690
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226397616
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9231
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226397615
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID171548
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID420237493
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID447549647
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419576306
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID452705
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID455222077

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