| abstract |
Tetrahydroisoquinoline analogs are provided which are useful in stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength. n The tetrahdroisoquinoline analogs thereof have the structure n n n wherein R 1 , R 2 , R 3 , R 3a , X 1 , X 2 , X 3 , X 4 , m and n are as described herein. |