http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002037270-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2562-0215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2562-0217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0428 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F13-0253 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-259 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J201-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J133-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J133-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J133-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J133-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J141-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-0408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-58 |
| filingDate | 2001-01-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e494037bc71c40d7e5fca94b9b4658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2f9c1786b05945c5c9fbc753c25ebab |
| publicationDate | 2002-03-28^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002037270-A1 |
| titleOfInvention | Bioadhesive compositions and wound dressings containing them |
| abstract | A method for the treatment and/or prophylaxis of conditions characterized by overstimulation of the tachykinin receptors, which method comprises the administration to a mammal in need thereof of an effective, non-toxic, pharmaceutically acceptable amount of a compound of formula (I), or a pharmaceutically acceptable solvate thereof, or a pharmaceutically acceptable salt thereof, wherein: Ar is an optionally substituted phenyl, naphthyl or C 5-7 cycloalkdienyl group, or an optionally substituted single or fused ring heterocyclic group, having aromatic character, containing from 5 to 12 ring atoms and comprising up to four heteroatoms in the or each ring selected from S, O, N; R is linear or branched C 1-8 alkyl, C 3-7 cycloalkyl, C 4-7 cycloalkylalkyl, optionally substituted phenyl or phenyl C 1-6 alkyl, an optionally substituted five-membered heteroaromatic ring comprising up to four heteroatoms selected from O and N, hydroxy C 1-6 alkyl, amino C 1-6 alkyl, C 1-6 alkylaminoalkyl, di C 1-6 alkylaminoalkyl, C 1-6 acylaminoalkkyl, C 1-6 alkoxyalkyl, C 1-6 alkylcarbonyl, carboxy, C 1-6 alkoxycarbonyl, C 1-6 alkoxycarbonyl, C 1-6 alkyl, aminocarbonyl, C 1-6 alkylaminocarbonyl, di C 1-6 alkylaminocarbonyl, halogeno C 1-6 alkyl; or is a group —(CH 2) p— when cyclized onto Ar, where p is 2 or 3. R1 and R2, which may be the same or different, are independently hydrogen or C 1-6 linear or branched alkyl, or together form a —(CH2)n— group in which n represents 3, 4 or 5; or R 1 together with R forms a group —(CH 2)q—, in which q is 2, 3, 4 or 5; R 3 and R 4, which may be the same or different, are independently hydrogen, C 1-6 linear or branched alkyl, C 1-6 alkenyl, aryl, C 1-6 alkoxy, hydroxy, halogen, nitro, cyano, carboxy, carboxamido, sulphonamido, C 1-6 alkoxycarbonyl, trifluoromethyl, acyloxy, phthalimido, amino, mono- and di-C 1-6 alkylamino, —O(CH 2)r—NT 2, in which r is 2, 3 or 4 and T is hydrogen or C 1-6 alkyl or it forms with the adjacent nitrogen a group (a) or (b), in which V and V 1 are independently hydrogen or oxygen and u is 0, 1 or 2; —O(CH 2 ) s—OW in which s is 2, 3 or 4 and W is hydrogen or C 1-6 alkyl; hydroxyalkyl, aminoalkyl, mono- or di-alkylaminoalkyl, alkylamino, alkylsulphonylamino, aminoacylamino, mono- or di-alkylaminoacylamino; with up to four R 3 substituents being present in the quinoline nucleus; or R 4 is a group —(CH 2 ) t — when cyclized onto R 5 as aryl, in which t is 1, 2 or 3; R 5 is branched or linear C 1-6 alkyl, C 3-7 cycloalkyl, C 4-7 cycloalkylalkyl, optionally substituted aryl, or an optionally substituted single or fused ring heterocyclic group, having aromatic character, containing from 5 to 12 ring atoms and comprising up to four heteroatoms in the or each ring selected from S, O, N; X is O, S, or N-CaN. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005181026-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006258788-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7927588-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005244629-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7731954-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183701-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6713538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007190122-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009081279-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6641569-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009169600-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007148117-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006275350-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006034816-A1 |
| priorityDate | 1998-07-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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