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filingDate 2001-05-14^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb4c0c7df4385f3be5989ec12aab1c48
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publicationDate 2002-04-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2002045578-A1
titleOfInvention Solution structure of TNFR-1 DD and uses thereof
abstract The present invention relates to the three dimensional solution structure of tumor necrosis factor receptor 1 death domain (TNFR-1 DD), as well as the identification and characterization of various binding active sites of TNFR-1 DD. Also provided for by the present invention are methods of utilizing the three dimensional structure for the design and selection of potent and selective inhibitors of TNF signaling pathways.
priorityDate 2000-05-22^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226413457
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ1X6Z6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO01382
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP40243
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID656894
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ1HN36
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ1X709

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