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filingDate 2002-03-01^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38e9802025c804c871516975f85e38fd
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publicationDate 2002-12-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2002187498-A1
titleOfInvention Skin substitutes for irritancy testing
abstract The present invention relates to in vitro cultured skin substitutes, preferably to in vitro cultured skin substitutes that have improved barrier function. In particular, the present invention relates to the use of such skin substitutes for irritancy testing. The present invention provides improved methods of screening compounds for irritancy activity, as well for identifying novel irritant responsive genes.
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