| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2001-04-02^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37f2adaea0c28af5e0045f71a4a109f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f831af34ee2c26f385f7fe130aef8d9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_649535c187cbc819f653c8faea161ada
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c89b6e56104beb546e25a1defb50a3c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65a08c0b63f85820130dcac2bb1626a3 |
| publicationDate |
2003-05-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003092000-A1 |
| titleOfInvention |
Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| abstract |
The invention provides criteria and methods for selecting optimum subsequence(s) from a target gene for targeting by a zinc finger protein. Some of the methods of target site selection seek to identify one or more target segments having a DNA motif containing one or more so-called D-able subsites having the sequence 5′NNGK3′. Other methods of the invention are directed to selection of target segments within target genes using a correspondence regime between different triplets of three bases and the three possible positions of a triplet within a nine-base site. In another aspect, the invention provides methods of designing zinc finger proteins that bind to a preselected target site. These methods can be used following the preselection of target sites according to the procedures and criteria described above. The methods of design use a database containing information about previously characterized zinc finger proteins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016076056-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2395081-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197892-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008188000-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9217026-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10907175-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110335640-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466271-B2 |
| priorityDate |
1999-01-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |