http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003144178-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
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filingDate 2001-04-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a83ab3b6d0ac56b6601c6f38e034be85
publicationDate 2003-07-31^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003144178-A1
titleOfInvention Method for inhibiting C-jun expression using JAK-3 inhibitors
abstract The invention provides a method for inhibiting c-jun activation in mammalian or avian cells comprising contacting the cells with a substance that inhibits the activity of Janus family kinase 3 (JAK-3). The invention also provides a therapeutic method for preventing or treating a pathological condition in a mammal wherein c-jun activation is implicated and inhibition of its activation is desired comprising administering to a mammal in need of such therapy, an effective amount of a substance that inhibits the activity of JAK-3. Novel compounds that are JAK-3 inhibitors, as well as pharmaceutical compositions comprising the compounds are also provided.
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