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filingDate 2003-02-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8169c9e7f4ea20177fa6d3fbd1911b84
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publicationDate 2003-08-21^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003157156-A1
titleOfInvention Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers
abstract A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered oxybutynin. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the drug through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations, drug delivery systems and methods of treatment are provided as well.
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