http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005025839-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-14 |
| filingDate | 2004-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_285e99c98cdfe52420ff47b8bdd7bee5 |
| publicationDate | 2005-02-03^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005025839-A1 |
| titleOfInvention | Formulation approach to enhance transporter-mediated drug uptake |
| abstract | Transporters are membrane proteins that translocate solutes across biological membranes. Active agents such as drugs, prodrugs, nutrients, nutraceuticals, and other bioactive substances are substrates for transporters. Some transporters require sodium to be co-transported with solute, in order to transport solute. This invention relates to a pharmaceutical formulation approach to enhance uptake of active agent by increasing the uptake of active agent by a sodium-dependent transporter, where sodium is fabricated with or co-administered with active agent. One example is the formulation of a dosage form containing the prodrug acyclovir valychenodeoxycholate, which targets the human apical sodium-dependent bile acid transporter, and sodium chloride to enhance active agent uptake from the gastrointestinal tract. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3393469-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8470543-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10857152-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10953011-B2 |
| priorityDate | 2003-07-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 242 of 242.