| abstract |
Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, n n nwherein, for example, HET is an N-linked 5-membered, fully or partially unsaturated heterocyclic ring, or an N-linked 6-membered di-hydro-heteroaryl ring; and Q is, for example, Q1 or Q2: n n nwherein R 2 and R 3 are independently hydrogen or fluoro; T is selected, for example, from a group of the formula (TA1) or (TA2): n n nwherein, for example, X 1m is O═ and X 2m is R 2s —(E) ms —N—; wherein E is an electron withdrawing group, for example, —SO 2 — or —CO—; and, for example, R 2s is hydrogen or (1-6C)alkyl; are useful as pharmaceutical agents; and processes for their manufacture and pharmaceutical compositions containing them are described. |