http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005049420-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-74
filingDate 2004-08-16^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41e4e74b88732ad52e2407b36713db10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a66d21d0bed8c0c502682b054e4e57e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b17ad29d4ca9bc2fe5af488d05549cab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a17ceeea7d756c4f807781ff388e1474
publicationDate 2005-03-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2005049420-A1
titleOfInvention Process for producing N-halogenated organic compounds
abstract The process enables highly effective N-halogenation of a compound having one or more halogenatable amido or imido functional groups in the molecule. The process involves, for example, concurrently feeding into a reactor (i) water, inorganic base, and the compound to be N-halogenated, e.g., a hydantoin, and a feed of (ii) a brominating agent and/or a chlorinating agent. The proportions of these feeds are such that the pH is kept at 5 or below or within a specified range e.g., 5.5-8.5 and one or more of the amido or imido nitrogen atoms is substituted by a bromine or chlorine atom. A feature of the process is that it can be conducted at elevated temperatures as high as about 90° C. without appreciable thermal decomposition of reactants or product. The resultant product continuously precipitates in high yield and purity. Moreover, products can be produced that are very pale yellow to almost pure white in appearance. Further, the process has been found capable of producing 1,3-dibromo-5,5-dimethylhydantoin with far larger particle sizes than previously produced on a commercial basis.
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