| abstract |
A process for the preparation of vinyl, aryl and heteroaryl acetic acids and their derivatives by the reaction of vinyl, aryl or heteroaryl boronic acids and their derivatives with α-halo- or α-pseudohaloacetic acids and their derivatives which bear a substituent selected from hydrogen, alkyl or vinyl, aryl and heteroaryl in 2-position in the presence of a palladium catalyst, a base and water. This process enables the preparation of a wide variety of functionalized vinyl, aryl and heteroaryl acetic acids and their derivatives. |