http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005177316-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd751f936595d36652c757d376119f9e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-40 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2004-09-21^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a9d60ec23a147d3f1eb0bbd1c76d17c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73b8c74f577fc9c318f7931174819a62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e9f69987cdcabd0eb6278b903eef85f |
| publicationDate | 2005-08-11^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005177316-A1 |
| titleOfInvention | Algorithm for estimating and testing association between a haplotype and quantitative phenotype |
| abstract | A method of estimating, in addition to haplotype frequencies and diplotype configurations, a means and a standard deviation determining a distribution of a quantitative phenotype by the diplotype on the basis of data on observed genotypes and phenotype data taking a continuous value. The method includes a step a of calculating the maximum likelihood (L 0max ) on the basis of genotype data and phenotype data taking a continuous value by using as parameters haplotype frequencies and a means and a standard deviation determining a distribution of a quantitative phenotype, under the hypothesis that there is no association between a diplotype configuration including a predetermined haplotype and a predetermined phenotype, and maximum likelihood estimates and the maximum likelihood (L max ) of haplotype frequencies and penetration rate obtained by maximizing the likelihood under the hypothesis that there is an association between the diplotype configuration including the predetermined haplotype and the phenotype distribution taking a continuous value, and a step b of obtaining the means and the standard deviation determining a distribution of a quantitative phenotype from the maximum likelihood estimates obtained in the step a. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007239416-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020133588-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103323878-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10235496-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11342048-B2 |
| priorityDate | 2003-09-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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